![]() ![]() Paired two-tailed Student’s t-tests were used, P= 0.0014. e, Pooled data of PPR and the normalized amplitudes of evoked EPSCs (n= 7/6, neurons/mice). d, Superimposed sample traces of evoked EPSCs by paired pulses of field stimulations before and after prolonged optogenetic stimulation. Paired two-tailed Student’s t-tests were used: AMPAR-EPSC, P= 0.0057 NMDAR-EPSC, P= 0.0064 and AMPAR/NMDAR ratio, P= 0.0508. Numbers of neurons/animals analyzed are indicated in bars. c, Pooled normalized data showing the amplitude of AMPAR-EPSCs (n= 11/8, neurons/mice), NMDAR-EPSCs (n= 8/6, neurons/mice) and ratios of AMPAR-EPSC/NMDAR-EPSC (n= 8/6, neurons/mice). b, Sample traces of evoked AMPAR-mediated (Vh =−70 mV) and NMDAR-mediated (Vh =+40 mV) EPSCs in dLS-LHA neurons via field stimulations before (control) and after 20-Hz, 2-min optogenetic stimulation of MCH axons expressing ChR2. a, RNAScope in situ hybridization result using probes against MCHR1 and vGAT. MCH enhances excitatory synaptic transmission in the dLS. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |